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O1-tert-butyl O2-methyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate

Boc-Hyp-OMe

CAS: 74844-91-0

Molecular Formula: C11H19NO5

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  5. O1-tert-butyl O2-methyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate

O1-tert-butyl O2-methyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate - Names and Identifiers

Name Boc-Hyp-OMe
Synonyms Boc-Hyp-OMe
N-BOC-4-HYDROXY-L-PROLINE METHYL ESTER
N-Boc-trans-4-hydroxy-L-prolinemethylester
Boc-trans-4-hydroxy-L-proline methyl ester
(2S,4R)-1-Boc-4-Hydroxy-Proline Methylester
N-BOC-trans-4-hydroxy-L-proline methyl ester
N-BOC-TRANS-4-HYDROXY-L-PROLINE METHYL ESTER
N-BOC-L-TRANS-4-HYDROXY-PROLINE METHYL ESTER
N-BOC-TRANS-4-HYDROXYL-L-PROLINE METHYL ESTER
N-T-BOC-TRANS-4-HYDROXY-L-PROLINE METHYL ESTER
N-ALPHA-T-BUTOXYCARBONYL-L-HYDROXYPROLINE METHYL ESTER
N-(tert-butoxycarbonyl)-cis-4-hydroxy-L-proline Methyl ester
N-(tert-Butoxycarbonyl)-trans-hydroxy-L-proline methyl ester
N-(TERT-BUTOXYCARBONYL)-TRANS-HYDROXYL-L-PROLINE METHYL ESTER
(2S,4R)-1-tert-butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate
O1-tert-butyl O2-methyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate
(2R,4R)-4-HYDROXY-PYRROLIDINE-1,2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER 2-METHYL ESTER
CAS 74844-91-0
EINECS 616-143-2
InChI InChI=1/C11H19NO5/c1-11(2,3)17-10(15)12-6-7(13)5-8(12)9(14)16-4/h7-8,13H,5-6H2,1-4H3/t7-,8+/m1/s1
InChIKey MZMNEDXVUJLQAF-SFYZADRCSA-N

O1-tert-butyl O2-methyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate - Physico-chemical Properties

Molecular FormulaC11H19NO5
Molar Mass245.27
Density1.216±0.06 g/cm3(Predicted)
Melting Point92-96 °C (lit.)
Boling Point132°C/0.05mmHg(lit.)
Specific Rotation(α)-65 º (c=1 CHCl3)
Flash Point156.55°C
Solubility Soluble in chloroform, dichloromethane and ethyl acetate.
Vapor Presure0mmHg at 25°C
AppearanceCrystal
ColorWhite to light beige
pKa14.27±0.40(Predicted)
Storage ConditionKeep in dark place,Sealed in dry,Room Temperature
Refractive Index1.501
MDLMFCD00076981

O1-tert-butyl O2-methyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate - Risk and Safety

Hazard SymbolsXn - Harmful
Harmful
Risk CodesR20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety DescriptionS24/25 - Avoid contact with skin and eyes.
S36 - Wear suitable protective clothing.
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany3
HS Code29339900
Hazard ClassIRRITANT

O1-tert-butyl O2-methyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate - Reference Information

LogP0.813 at 25℃
Introduction N-Boc-trans-4-hydroxy-l-proline methyl ester is a carboxylic acid ester organic substance, it can be used to synthesize a Met-based For-Met-Leu-Phe-OMe(fMLF-OMe) analog with residues replaced by a 4-aminoproline scaffold.
Use N-Boc-trans-4-hydroxy-l-proline methyl ester is an amino acid derivative, it can be used as a pharmaceutical intermediate.
Last Update：2024-04-09 21:04:16
O1-tert-butyl O2-methyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate
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Sichuan Hengkang Science and Technology Development Co.,Ltd.
Featured ProductsSpot supply
Product Name: N-Boc-trans-4-Hydroxy-L-proline methyl ester Request for quotation
CAS: 74844-91-0
Tel: +86-18980427282
Email: hk999@hengkangtech.com
Mobile: +86-18980427282
QQ: 1525088774 Click to send a QQ message
Wechat: 18980427282
WhatsApp: 15008222507
Linkedin: linkedin.com/in/teresa-li-806a0095
Product List: View Catalog
Nantong Reform Petro-Chemical CO., LTD.
Spot supply
Product Name: Boc-Hyp-OMe Request for quotation
CAS: 74844-91-0
Tel: +86-17551318830
Email: r@reformchem.com­
Mobile: +86-17551318830
QQ: 3785839865 Click to send a QQ messageSend QQ message
Jiangsu Pules Biotechnology Co.,Ltd.
Product Name: Boc-Hyp-OMe Request for quotation
CAS: 74844-91-0
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
Hubei YoungXin Pharmaceutical Tech Co.,Ltd.
Product Name: MRTX-1133 Impurity 6 Request for quotation
CAS: 74844-91-0
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052 Click to send a QQ message
Wechat: 15671228036
Shanghai Yuanye Bio-Technology Co., Ltd.
Spot supply
Product Name: BOC-L-Hydroxyproline methyl ester Visit Supplier Webpage Request for quotation
CAS: 74844-91-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
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O1-tert-butyl O2-methyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate
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